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(+)-cis-2-Aminomethylcyclopropane carboxylic acid
Stereo, skeletal formula of (+)-cis-2-aminomethylcyclopropane carboxylic acid | ||
C=black, H=white, O=red, N=blue | ||
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Systematic IUPAC name
(1S,2R)-2-(Aminomethyl)cyclopropane-1-carboxylic acid[1] | |
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36489-13-1 7px | |
ChEMBL | ChEMBL230115 7px | |
ChemSpider | 1236854 7px | |
Jmol-3D images | Image | |
PubChem | Template:Chembox PubChem/format | |
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C5H9NO2 | |
Molar mass | Lua error in Module:Math at line 495: attempt to index field 'ParserFunctions' (a nil value). g·mol−1 | |
Density | 1.275 g/mL | |
Boiling point | Script error: No such module "convert". | |
log P | −0.721 | |
Acidity (pKa) | 4.157 | |
Basicity (pKb) | 9.840 | |
Isoelectric point | 7.01 | |
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Related cycloalkanes
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ACPD |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | ||
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Infobox references | ||
(+)-cis-2-Aminomethylcyclopropane carboxylic acid ((+)-CAMP) is a GABA agonist selective for the GABAA-ρ (previously known as GABAC) subtype.[2][3]
References
- ^ "AC1LT400 - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 11 July 2005. Identification and Related Records. Retrieved 7 October 2011.
- ^ Duke, RK; Chebib, M; Balcar, VJ; Allan, RD; Mewett, KN; Johnston, GA (2000). "(+)- and (−)-cis-2-aminomethylcyclopropanecarboxylic acids show opposite pharmacology at recombinant rho(1) and rho(2) GABA(C) receptors". Journal of Neurochemistry 75 (6): 2602–10. PMID 11080214.
- ^ Carland, JE; Moorhouse, AJ; Barry, PH; Johnston, GA; Chebib, M (2004). "Charged residues at the 2' position of human GABAC rho 1 receptors invert ion selectivity and influence open state probability". The Journal of Biological Chemistry 279 (52): 54153–60. PMID 15485818. doi:10.1074/jbc.M410625200.
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