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Open Access Articles- Top Results for (%2B)-cis-2-Aminomethylcyclopropane carboxylic acid

(+)-cis-2-Aminomethylcyclopropane carboxylic acid

(+)-cis-2-Aminomethylcyclopropane carboxylic acid
Stereo, skeletal formula of (+)-cis-2-aminomethylcyclopropane carboxylic acid
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Systematic IUPAC name
(1S,2R)-2-(Aminomethyl)cyclopropane-1-carboxylic acid[1]
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36489-13-1 7pxN
ChEMBL ChEMBL230115 7pxY
ChemSpider 1236854 7pxY
Jmol-3D images Image
PubChem Template:Chembox PubChem/format
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C5H9NO2
Molar mass Lua error in Module:Math at line 495: attempt to index field 'ParserFunctions' (a nil value). g·mol−1
Density 1.275 g/mL
Boiling point Script error: No such module "convert".
log P −0.721
Acidity (pKa) 4.157
Basicity (pKb) 9.840
Isoelectric point 7.01
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Related cycloalkanes
ACPD
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 14pxN verify (what is10pxY/10pxN?)
Infobox references
Not to be confused with Cyclic adenosine monophosphate.

(+)-cis-2-Aminomethylcyclopropane carboxylic acid ((+)-CAMP) is a GABA agonist selective for the GABAA (previously known as GABAC) subtype.[2][3]

References

  1. ^ "AC1LT400 - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 11 July 2005. Identification and Related Records. Retrieved 7 October 2011. 
  2. ^ Duke, RK; Chebib, M; Balcar, VJ; Allan, RD; Mewett, KN; Johnston, GA (2000). "(+)- and (−)-cis-2-aminomethylcyclopropanecarboxylic acids show opposite pharmacology at recombinant rho(1) and rho(2) GABA(C) receptors". Journal of Neurochemistry 75 (6): 2602–10. PMID 11080214. 
  3. ^ Carland, JE; Moorhouse, AJ; Barry, PH; Johnston, GA; Chebib, M (2004). "Charged residues at the 2' position of human GABAC rho 1 receptors invert ion selectivity and influence open state probability". The Journal of Biological Chemistry 279 (52): 54153–60. PMID 15485818. doi:10.1074/jbc.M410625200. 



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