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Open Access Articles- Top Results for 1,3-Difluoro-2-propanol

1,3-Difluoro-2-propanol

1,3-Difluoro-2-propanol
200px
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IUPAC name
1,3-Difluoro-2-propanol
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453-13-4 7pxN
ChemSpider 61300 7pxY
Jmol-3D images Image
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PubChem Template:Chembox PubChem/format
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C3H6F2O
Molar mass Lua error in Module:Math at line 495: attempt to index field 'ParserFunctions' (a nil value). g·mol−1
Density 1.24 g/cm3 (at 25 °C) [1]
Boiling point Script error: No such module "convert".
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Flash point Script error: No such module "convert".
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

1,3-Difluoro-2-propanol is a metabolic poison which disrupts the citric acid cycle and is used as a rodenticide, similar to sodium fluoroacetate. It is the main ingredient (along with 1-chloro-3-fluoro-2-propanol) in the rodenticide product Gliftor which was widely used in the former USSR.[2][3][4]

References

  1. ^ Sigma Aldrich
  2. ^ Buklan AI, Kravets AF (1986). "[Gliftor poisoning]". Sud. Med. Ekspert. (in Russian) 29 (1): 55–6. PMID 3961873. 
  3. ^ Feldwick MG, Noakes PS, Prause U, Mead RJ, Kostyniak PJ (1998). "The biochemical toxicology of 1,3-difluoro-2-propanol, the major ingredient of the pesticide gliftor: the potential of 4-methylpyrazole as an antidote". J. Biochem. Mol. Toxicol. 12 (1): 41–52. PMID 9414486. doi:10.1002/(SICI)1099-0461(1998)12:1<41::AID-JBT6>3.0.CO;2-P. 
  4. ^ Menon KI, Feldwick MG, Noakes PS, Mead RJ (2001). "The mode of toxic action of the pesticide gliftor: the metabolism of 1,3-difluoroacetone to (−)-erythro-fluorocitrate". J. Biochem. Mol. Toxicol. 15 (1): 47–54. PMID 11170315. doi:10.1002/1099-0461(2001)15:1<47::AID-JBT6>3.0.CO;2-E.