Open Access Articles- Top Results for 17-Phenylandrostenol


Systematic (IUPAC) name
(3R,5S,8R,9S,10S,13S,14S)-10,13-dimethyl-17-phenyl- 2,3,4,5,6,7,8,9,11,12,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Clinical data
694438-95-4 7pxN
PubChem CID 25068278
ChemSpider 21475142 7pxY
Synonyms (3α,5α)-17-Phenyl-androst-16-en-3-ol
Chemical data
Formula C25H34O
350.535 g/mol
 14pxN (what is this?)  (verify)

17-Phenylandrostenol (17-PA) is a steroid drug which binds to GABAA receptors. It acts as an antagonist against the sedative effects of neuroactive steroids, but has little effect when administered by itself, and does not block the effects of benzodiazepines or barbiturates.[1][2]


  1. ^ Mennerick S, He Y, Jiang X, Manion BD, Wang M, Shute A, Benz A, Evers AS, Covey DF, Zorumski CF (May 2004). "Selective antagonism of 5alpha-reduced neurosteroid effects at GABA(A) receptors". Molecular Pharmacology 65 (5): 1191–7. PMID 15102947. doi:10.1124/mol.65.5.1191. 
  2. ^ Kelley SP, Alan JK, O'Buckley TK, Mennerick S, Krishnan K, Covey DF, Leslie Morrow A (October 2007). "Antagonism of neurosteroid modulation of native γ-aminobutyric acid receptors by (3α,5α)-17-phenylandrost-16-en-3-ol". European Journal of Pharmacology 572 (2–3): 94–101. PMC 2098702. PMID 17658511. doi:10.1016/j.ejphar.2007.06.028. 

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