Open Access Articles- Top Results for 2-Methyl-5-hydroxytryptamine


File:2-Methyl-5-hydroxytryptamine - 2.png
Systematic (IUPAC) name
Clinical data
78263-90-8 7pxN
PubChem CID 1574
IUPHAR ligand 218
ChemSpider 1518 7pxY
KEGG C13665 7pxY
ChEBI CHEBI:31085 7pxY
ChEMBL CHEMBL266591 7pxY
Chemical data
Formula C11H14N2O
190.242 g/mol
 14pxN (what is this?)  (verify)

2-Methyl-5-hydroxytryptamine (2-Methylserotonin, 2-Methyl-5-HT) is a tryptamine derivative closely related to the neurotransmitter serotonin which acts as a moderately selective full agonist at the 5-HT3 receptor.[1][2][3]

See also


  1. ^ Elz S, Zimmermann H, Rehse K. (1993). "Selectivity of sterically fixed tryptamine and 5-methoxytryptamine derivatives for serotonin receptor subtypes, II: Structure-activity relationships and in vitro pharmacology of N-alkyl- and N,N-dialkyl-3- indolylbicyclo-[2.2.1]-heptane-2-amines.". Arch Pharm (Weinheim). 326 (11): 893–899. PMID 8274071. doi:10.1002/ardp.19933261110. 
  2. ^ Craig DA, Eglen RM, Walsh LK, Perkins LA, Whiting RL, Clarke DE. (1990). "5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum.". Naunyn Schmiedebergs Arch Pharmacol. 342 (1): 9–16. PMID 2402303. doi:10.1007/bf00178965. 
  3. ^ Glennon RA, Dukat M, Westkaemper RB (2000-01-01). "Serotonin Receptor Subtypes and Ligands". American College of Neurophyscopharmacology. Archived from the original on 21 April 2008. Retrieved 2008-04-11. 

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