|This article relies too much on references to primary sources. (December 2007)|
|Systematic (IUPAC) name|
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2C-F, or 4-fluoro-2,5-dimethoxyphenethylamine, is a lesser-known psychedelic drug of the 2C family. It was first synthesized by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved), the minimum dosage is listed as 250 mg. 2C-F may be found as a brownish freebase oil, or as a white crystalline hydrochloride salt.
Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-F.
At a dose of 250 milligrams, 2C-F produces modest closed-eye visuals accompanied by lethargy. The amphetamine analogue DOF is likely to be more active than the phenethylamine derivative 2C-F, and in animal trials DOF was found to be 1/6 the activity of the potent hallucinogen DOI, which would make an active dose of DOF likely to be in the 6-18 milligram range, although it is not known to have been tested in humans.