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Open Access Articles- Top Results for 3,4-Dihydroxystyrene

3,4-Dihydroxystyrene

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3,4-Dihydroxystyrene
File:3,4-Dihydroxystyrene.png
File:3,4-dihydroxystyrene-3D-balls.png
Systematic (IUPAC) name
4-vinylbenzene-1,2-diol
Clinical data
  • Uncontrolled
Identifiers
6053-02-7 7pxN
None
PubChem CID 151398
ChemSpider 133430 7pxY
KEGG C06224 7pxY
Chemical data
Formula C8H8O2
136.15 g/mol
 14pxN (what is this?)  (verify)

3,4-Dihydroxystyrene (DHS) is a centrally-acting inhibitor of the enzyme phenylalanine hydroxylase (PH).[1] It is likely that DHS and other PH inhibitors will never have clinical applications on account of their capacity for inducing hyperphenylalaninemia and phenylketonuria.

See also

References

  1. ^ Koizumi S, Matsushima Y, Nagatsu T, Iinuma H, Takeuchi T, Umezawa H (September 1984). "3,4-dihydroxystyrene, a novel microbial inhibitor for phenylalanine hydroxylase and other pteridine-dependent monooxygenases". Biochimica Et Biophysica Acta 789 (2): 111–8. PMID 6148105. doi:10.1016/0167-4838(84)90194-8. 

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