|Ball-and-stick model of the 3-fluoroamphetamine molecule|
|Systematic (IUPAC) name|
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3-Fluoroamphetamine (3-FA; PAL-353) is a stimulant drug from the amphetamine family which acts as a monoamine releaser with similar potency to methamphetamine but more selectivity for dopamine and noradrenaline release over serotonin. It is self-administered by mice to a similar extent to related drugs such as 4-fluoroamphetamine and 3-methylamphetamine.
- 2-Fluoroamphetamine (2-FA)
- 3-Fluoroethamphetamine (3-FEA)
- 3-Fluoromethamphetamine (3-FMA)
- 3-Hydroxyamphetamine (Gepefrine)
- 3-Methylamphetamine (3-MA)
- 3-Methoxyamphetamine (3-MeOA)
- 3-Trifluoromethylamphetamine (Norfenfluramine)
- 4-Fluoroamphetamine (4-FA)
- Negus, SS; Mello, NK; Blough, BE; Baumann, MH; Rothman, RB (2007). "Monoamine releasers with varying selectivity for dopamine/norepinephrine versus serotonin release as candidate "agonist" medications for cocaine dependence: studies in assays of cocaine discrimination and cocaine self-administration in rhesus monkeys". The Journal of Pharmacology and Experimental Therapeutics 320 (2): 627–36. PMID 17071819. doi:10.1124/jpet.106.107383.
- Wee, S; Anderson, KG; Baumann, MH; Rothman, RB; Blough, BE; Woolverton, WL (2005). "Relationship between the serotonergic activity and reinforcing effects of a series of amphetamine analogs". The Journal of Pharmacology and Experimental Therapeutics 313 (2): 848–54. PMID 15677348. doi:10.1124/jpet.104.080101.