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4-Benzylpiperidine
File:4-Benzylpiperidine.png | |
Systematic (IUPAC) name | |
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4-(phenylmethyl)piperidine | |
Clinical data | |
Identifiers | |
31252-42-3 | |
PubChem | CID 31738 |
ChemSpider | 29432 7px |
ChEMBL | CHEMBL144129 7px |
Chemical data | |
Formula | C12H17N |
175.270 g/mol | |
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14px (what is this?) (verify) |
4-Benzylpiperidine is a drug and research chemical used in scientific studies. It acts as a monoamine releasing agent with 20- to 48-fold selectivity for releasing dopamine versus serotonin.[1] It has a fast onset of action and a short duration.[1] It also functions as a monoamine oxidase inhibitor (MAOI) with preference for MAO-A.[2]
See also
References
- ^ a b Negus SS, Baumann MH, Rothman RB, Mello NK, Blough BE. (2009). "Selective suppression of cocaine- versus food-maintained responding by monoamine releasers in rhesus monkeys: benzylpiperazine, (+)phenmetrazine, and 4-benzylpiperidine.". J Pharmacol Exp Ther. 329 (1): 272–281. PMC 2670586. PMID 19151247. doi:10.1124/jpet.108.143701.
- ^ Arai Y, Hamamichi N, Kinemuchi H. (1986). "Time-dependent inhibition of rat brain monoamine oxidase by an analogue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine.". Neurosci Lett. 70 (2): 255–260. PMID 3490636. doi:10.1016/0304-3940(86)90473-8.
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