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4-Benzylpiperidine

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4-Benzylpiperidine
File:4-Benzylpiperidine.png
Systematic (IUPAC) name
4-(phenylmethyl)piperidine
Clinical data
Identifiers
31252-42-3
PubChem CID 31738
ChemSpider 29432 7pxY
ChEMBL CHEMBL144129 7pxY
Chemical data
Formula C12H17N
175.270 g/mol
 14pxY (what is this?)  (verify)

4-Benzylpiperidine is a drug and research chemical used in scientific studies. It acts as a monoamine releasing agent with 20- to 48-fold selectivity for releasing dopamine versus serotonin.[1] It has a fast onset of action and a short duration.[1] It also functions as a monoamine oxidase inhibitor (MAOI) with preference for MAO-A.[2]

See also

References

  1. ^ a b Negus SS, Baumann MH, Rothman RB, Mello NK, Blough BE. (2009). "Selective suppression of cocaine- versus food-maintained responding by monoamine releasers in rhesus monkeys: benzylpiperazine, (+)phenmetrazine, and 4-benzylpiperidine.". J Pharmacol Exp Ther. 329 (1): 272–281. PMC 2670586. PMID 19151247. doi:10.1124/jpet.108.143701. 
  2. ^ Arai Y, Hamamichi N, Kinemuchi H. (1986). "Time-dependent inhibition of rat brain monoamine oxidase by an analogue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine.". Neurosci Lett. 70 (2): 255–260. PMID 3490636. doi:10.1016/0304-3940(86)90473-8. 



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