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Open Access Articles- Top Results for AL-38022A

AL-38022A

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AL-38022A
180px
Systematic (IUPAC) name
(S)-2-(8,9-dihydro-7H-pyrano[2,3-g]indazol-1-yl)-1-methylethylamine
Clinical data
Identifiers
478132-11-5 7pxN
PubChem CID 22496603
ChemSpider 26286943 7pxY
Chemical data
Formula C13H17N3O
231.293 g/mol
Physical data
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AL-38022A is an indazole derivative drug which is one of a range of similar drugs developed for scientific research and with some possible clinical applications. It acts as a potent and selective agonist for the 5-HT2 family of serotonin receptors, with highest binding affinity for the 5-HT2C subtype and around 4x less affinity for 5-HT2A and 5-HT2B. In drug discrimination tests on animals, it fully substituted for both DOM and 5-MeO-DMT.[1]

See also

References

  1. ^ May, JA; Sharif, NA; Chen, HH; Liao, JC; Kelly, CR; Glennon, RA; Young, R; Li, JX; Rice, KC; France, CP (2009). "Pharmacological properties and discriminative stimulus effects of a novel and selective 5-HT2 receptor agonist AL-38022A (S)-2-(8,9-dihydro-7H-pyrano2,3-gindazol-1-yl)-1-methylethylamine". Pharmacology, Biochemistry, and Behavior 91 (3): 307–14. PMID 18718483. doi:10.1016/j.pbb.2008.07.015. 

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