Adverts

Open Access Articles- Top Results for ALDH1A3

ALDH1A3

Template:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/row
Identifiers
SymbolsALDH1A3 ; ALDH1A6; ALDH6; MCOP8; RALDH3
External IDsOMIM600463 MGI1861722 HomoloGene68080 ChEMBL: 3579 GeneCards: ALDH1A3 Gene
EC number1.2.1.5
Orthologs
SpeciesHumanMouse
Entrez22056847
EnsemblENSG00000184254ENSMUSG00000015134
UniProtP47895Q9JHW9
RefSeq (mRNA)NM_000693NM_053080
RefSeq (protein)NP_000684NP_444310
Location (UCSC)Chr 15:
101.4 – 101.46 Mb
Chr 7:
66.39 – 66.43 Mb
PubMed search[1][2]

Aldehyde dehydrogenase 1 family, member A3 also known as ALDH1A3 is an enzyme that in humans is encoded by the ALDH1A3 gene,[1]

Function

Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme encoded by this gene uses retinal as a substrate, either in a free or a cellular retinol-binding protein form.[2]

References

  1. ^ Hsu LC, Chang WC, Hiraoka L, Hsieh CL (November 1994). "Molecular cloning, genomic organization, and chromosomal localization of an additional human aldehyde dehydrogenase gene, ALDH6". Genomics 24 (2): 333–41. PMID 7698756. doi:10.1006/geno.1994.1624. 
  2. ^ "Entrez Gene: ALDH1A3". 

Further reading

</dl>

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



Template:Gene-15-stub