Open Access Articles- Top Results for ALDH1L2


SymbolsALDH1L2 ; mtFDH
External IDsOMIM613584 MGI2444680 HomoloGene51942 GeneCards: ALDH1L2 Gene
EC number1.5.1.6
RefSeq (mRNA)NM_001034173NM_153543
RefSeq (protein)NP_001029345NP_705771
Location (UCSC)Chr 12:
105.41 – 105.48 Mb
Chr 10:
83.49 – 83.53 Mb
PubMed search[1][2]

Aldehyde dehydrogenase 1 family, member L2 also known as ALDH1L2 is an enzyme that in humans is encoded by the ALDH1L2 gene.[1][2] ALDH1L2 is the mitochondrial isoform of a similar enzyme, ALDH1L1, which converts 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide.[3][4]


  1. ^ Strausberg RL, Feingold EA, Grouse LH et al. (December 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241. PMID 12477932. doi:10.1073/pnas.242603899. 
  2. ^ Ota T, Suzuki Y, Nishikawa T et al. (January 2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285. 
  3. ^ Krupenko NI, Dubard ME, Strickland KC, Moxley KM, Oleinik NV, Krupenko SA. "ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase." J Biol Chem. 2010 Jul 23;285(30):23056-63.
  4. ^ Strickland KC, Krupenko NI, Dubard ME, Hu CJ, Tsybovsky Y, Krupenko SA. "Enzymatic properties of ALDH1L2, a mitochondrial 10-formyltetrahdyrofolate dehydrogenase." Chem Biol Interact. 2011 May 30;191(1-3):129-36.

Further reading


Lua error in package.lua at line 80: module 'Module:Buffer' not found.