Adverts

Open Access Articles- Top Results for AM-905

AM-905

</th></tr>
AM-905
240px
Systematic (IUPAC) name
(6aR,9R,10aR)-3-[(E)-hept-1-enyl]-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
Clinical data
Identifiers
 7pxY
PubChem CID 9998522
ChemSpider 8174103 7pxY
ChEMBL CHEMBL127848 7pxY
Chemical data
Formula C23H34O3
358.513 g/mol
 14pxY (what is this?)  (verify)

AM-905 is an analgesic drug which is a cannabinoid agonist with a conformationally restricted side chain. It is a potent and reasonably selective agonist for the CB1 cannabinoid receptor, with a Ki of 1.2nM at CB1 and 5.3nM at CB2.[1]

References

  1. ^ Papahatjis DP, Kourouli T, Abadji V, Goutopoulos A, Makriyannis A. Pharmacophoric requirements for cannabinoid side chains: multiple bond and C1'-substituted delta 8-tetrahydrocannabinols. Journal of Medicinal Chemistry. 1998 Mar 26;41(7):1195-200. PMID 9544219


Lua error in package.lua at line 80: module 'Module:Buffer' not found.