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AQP5

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Identifiers
SymbolsAQP5 ; AQP-5; PPKB
External IDsOMIM600442 MGI106215 HomoloGene20398 IUPHAR: 692 GeneCards: AQP5 Gene
RNA expression pattern
File:PBB GE AQP5 213611 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez36211830
EnsemblENSG00000161798ENSMUSG00000044217
UniProtP55064Q9WTY4
RefSeq (mRNA)NM_001651NM_009701
RefSeq (protein)NP_001642NP_033831
Location (UCSC)Chr 12:
50.36 – 50.36 Mb
Chr 15:
99.59 – 99.59 Mb
PubMed search[1][2]

Aquaporin-5 is a protein that in humans is encoded by the AQP5 gene.[1][2]

Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13.[2]

See also

References

  1. ^ Lee MD, Bhakta KY, Raina S, Yonescu R, Griffin CA, Copeland NG, Gilbert DJ, Jenkins NA, Preston GM, Agre P (Jun 1996). "The human Aquaporin-5 gene. Molecular characterization and chromosomal localization". J Biol Chem 271 (15): 8599–604. PMID 8621489. doi:10.1074/jbc.271.15.8599. 
  2. ^ a b "Entrez Gene: AQP5 aquaporin 5". 

Further reading

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External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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