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AQP9

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Identifiers
SymbolsAQP9 ; AQP-9; HsT17287; SSC1
External IDsOMIM602914 MGI1891066 HomoloGene41405 IUPHAR: 696 GeneCards: AQP9 Gene
Orthologs
SpeciesHumanMouse
Entrez36664008
EnsemblENSG00000103569ENSMUSG00000032204
UniProtO43315Q9JJJ3
RefSeq (mRNA)NM_020980NM_001271843
RefSeq (protein)NP_066190NP_001258772
Location (UCSC)Chr 15:
58.43 – 58.48 Mb
Chr 9:
71.11 – 71.17 Mb
PubMed search[1][2]

Aquaporin-9 is a protein that in humans is encoded by the AQP9 gene.[1]

The aquaporins/major intrinsic protein are a family of water-selective membrane channels. Aquaporin 9 has greater sequence similarity with AQP3 and AQP7 and they may be a subfamily. Aquaporin 9 allows passage of a wide variety of noncharged solutes. AQP9 stimulates urea transport and osmotic water permeability; there are contradicting reports about its role in providing glycerol permeability. Aquaporin 9 may also have some role in specialized leukocyte functions such as immunological response and bactericidal activity.[1]

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