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Open Access Articles- Top Results for ATP11B

ATP11B

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Identifiers
SymbolsATP11B ; ATPIF; ATPIR
External IDsOMIM605869 MGI1923545 HomoloGene32919 IUPHAR: 866 GeneCards: ATP11B Gene
EC number3.6.3.1
RNA expression pattern
File:PBB GE ATP11B 212536 at tn.png
File:PBB GE ATP11B gnf1h02491 at tn.png
File:PBB GE ATP11B gnf1h02492 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez2320076295
EnsemblENSG00000058063ENSMUSG00000037400
UniProtQ9Y2G3Q6DFW5
RefSeq (mRNA)NM_014616NM_029570
RefSeq (protein)NP_055431NP_083846
Location (UCSC)Chr 3:
182.51 – 182.64 Mb
Chr 3:
35.75 – 35.86 Mb
PubMed search[1][2]

Probable phospholipid-transporting ATPase IF is an enzyme that in humans is encoded by the ATP11B gene.[1][2][3]

Function

P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[3]

References

  1. ^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N et al. (Feb 1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research 6 (1): 63–70. PMID 10231032. doi:10.1093/dnares/6.1.63. 
  2. ^ Halleck MS, Lawler JF JR, Blackshaw S, Gao L, Nagarajan P, Hacker C et al. (Nov 1999). "Differential expression of putative transbilayer amphipath transporters". Physiological Genomics 1 (3): 139–50. PMID 11015572. 
  3. ^ a b "Entrez Gene: ATP11B ATPase, Class VI, type 11B". 

Further reading

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