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Open Access Articles- Top Results for ATP12A

ATP12A

Template:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/row
Identifiers
SymbolsATP12A ; ATP1AL1
External IDsOMIM182360 MGI1926943 HomoloGene68197 IUPHAR: 850 ChEMBL: 2933 GeneCards: ATP12A Gene
EC number3.6.3.10
RNA expression pattern
File:PBB GE ATP12A 207367 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez479192113
EnsemblENSG00000075673ENSMUSG00000022229
UniProtP54707Q9Z1W8
RefSeq (mRNA)NM_001185085NM_138652
RefSeq (protein)NP_001172014NP_619593
Location (UCSC)Chr 13:
25.25 – 25.29 Mb
Chr 14:
56.37 – 56.39 Mb
PubMed search[1][2]

ATPase, H+/K+ transporting, nongastric, alpha polypeptide (also known as ATP12A) is a protein that in humans is encoded by the ATP12A gene.[1][2][3]

Function

The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This gene encodes a catalytic subunit of the ouabain-sensitive H+/K+ -ATPase that catalyzes the hydrolysis of ATP coupled with the exchange of H+ and K+ ions across the plasma membrane. It is also responsible for potassium absorption in various tissues.[1]

References

  1. ^ a b "Entrez Gene: ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide". 
  2. ^ Sverdlov VE, Kostina MB, Modyanov NN (March 1996). "Genomic organization of the human ATP1AL1 gene encoding a ouabain-sensitive H,K-ATPase". Genomics 32 (3): 317–27. PMID 8838794. doi:10.1006/geno.1996.0125. 
  3. ^ Yang-Feng TL, Schneider JW, Lindgren V, Shull MM, Benz EJ, Lingrel JB, Francke U (February 1988). "Chromosomal localization of human Na+, K+-ATPase alpha- and beta-subunit genes". Genomics 2 (2): 128–38. PMID 2842249. doi:10.1016/0888-7543(88)90094-8. 

Further reading

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