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ATP5G1

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Identifiers
SymbolsATP5G1 ; ATP5A; ATP5G
External IDsOMIM603192 MGI107653 HomoloGene38017 GeneCards: ATP5G1 Gene
RNA expression pattern
File:PBB GE ATP5G1 208972 s at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez51611951
EnsemblENSG00000159199ENSMUSG00000006057
UniProtP05496Q9CR84
RefSeq (mRNA)NM_001002027NM_001161419
RefSeq (protein)NP_001002027NP_001154891
Location (UCSC)Chr 17:
48.89 – 48.9 Mb
Chr 11:
96.07 – 96.08 Mb
PubMed search[1][2]

ATP synthase lipid-binding protein, mitochondrial is an enzyme that in humans is encoded by the ATP5G1 gene.[1][2]

Function

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding the same protein have been identified.[2]

References

Further reading

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