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Open Access Articles- Top Results for Aceglutamide

Aceglutamide

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Aceglutamide
Stereo, skeletal formula of aceglutamide (S)
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IUPAC name
N2-Acetylglutamine[citation needed]
Other names
α-N-Acetylglutamine[citation needed]
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2490-97-3 S 7pxY
ChemSpider 23836 7pxY
392045 R 7pxY
158492 S 7pxY
DrugBank DB04167 7pxY
EC number 219-647-7
Jmol-3D images Image
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KEGG D07063 7pxY
MeSH aceglutamide
PubChem Template:Chembox PubChem/formatTemplate:Chembox PubChem/formatTemplate:Chembox PubChem/format
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C7H12N2O4
Molar mass Lua error in Module:Math at line 495: attempt to index field 'ParserFunctions' (a nil value). g·mol−1
Appearance White crystals
Melting point Script error: No such module "convert".
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Related alkanoic acids
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Aceglutamide is a psychostimulant and nootropic[1] used to improve memory and concentration.[2] Chemically, it is the acetyl derivative of the amino acid L-glutamine.

The salt aceglutamide aluminum (also known as KW-110 and Glumal) is effective in the treatment of ulcers.[3][4][5][6]

Aceglutamide can also be used as a liquid-stable source of glutamine to prevent damage from protein energy malnutrition.[7][8][9]

References

  1. ^ Merck Index, 11th Edition, 21
  2. ^ Macdonald, F, ed. (1997). Dictionary of pharmacological agents. p. A-00018. ISBN 978-0-412-46630-4. 
  3. ^ Ito, M; Yokochi, E; Kobayashi, C; Suzuki, Y (1982). "Studies on defensive factors of experimental ulcers (2). Increasing action of aceglutamide aluminum on defensive factors in acetic acid ulcers of rats (author's transl)". Nihon yakurigaku zasshi. Folia pharmacologica Japonica 79 (4): 327–34. PMID 7095654. 
  4. ^ Harada, Masatoshi; Yano, Shingo (1974). "Inhibitory effect of N-acetyl-L-glutamine aluminum complex (KW-110) and related compounds on gastric erosion and motility in stressed animals". Oyo Yakuri 8 (1): 1–6. 
  5. ^ Varas Lorenzo, MJ; López Martínez, A; Gordillo Bernal, J; Mundet Surroca, J (1991). "Comparative study of 3 drugs (aceglutamide aluminum, zinc acexamate, and magaldrate) in the long-term maintenance treatment (1 year) of peptic ulcer". Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 80 (2): 91–4. PMID 1790087. 
  6. ^ Tanaka, H; Shuto, K; Marumo, H (1982). "Effect of N-acetyl-L-glutamine aluminum complex (KW-110), an antiulcer agent, on the non-steroidal anti-inflammatory drug-induced exacerbation of gastric ulcer in rats". Japanese journal of pharmacology 32 (2): 307–13. PMID 7098147. doi:10.1254/jjp.32.307. 
  7. ^ Lopez-Pedrosa Jose M; Manzano Manuel; Baxter Jeffrey H; Rueda Ricardo (2007). "N-acetyl-L-glutamine, a liquid-stable source of glutamine, partially prevents changes in body weight and on intestinal immunity induced by protein energy malnutrition in pigs". Digestive diseases and sciences 52 (3): 650–658. PMID 17253138. doi:10.1007/s10620-006-9500-y. 
  8. ^ JP 10101576 
  9. ^ US 2003099722 


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