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Open Access Articles- Top Results for Acetohexamide

Acetohexamide

Not to be confused with acetazolamide.
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Acetohexamide
File:Acetohexamide.svg
File:Acetohexamide ball-and-stick.png
Systematic (IUPAC) name
1-[(4-acetylbenzene)sulfonyl]-3-cyclohexylurea 4-acetyl-N-(cyclohexylcarbamoyl)benzenesulfonamide
Clinical data
Trade names Dymelor
AHFS/Drugs.com Micromedex Detailed Consumer Information
MedlinePlus a602021
Pharmacokinetic data
Protein binding 90%
Identifiers
968-81-0 7pxY
A10BB31
PubChem CID 1989
DrugBank DB00414 7pxY
ChemSpider 1912 7pxY
UNII QGC8W08I6I 7pxY
KEGG D00219 7pxY
ChEBI CHEBI:28052 7pxY
ChEMBL CHEMBL1589 7pxY
Chemical data
Formula C15H20N2O4S
324.395 g/mol
 14pxY (what is this?)  (verify)

Acetohexamide (trade name Dymelor) is a first-generation sulfonylurea medication used to treat diabetes mellitus type 2, particularly in people whose diabetes cannot be controlled by diet alone.

Mechanism of action

Acetohexamide lowers blood sugar by stimulating the pancreas to secrete insulin and helping the body use insulin efficiently.[1] The pancreas must produce insulin for this medication to work. For this reason, acetohexamide is not used to treat diabetes mellitus type 1.

Risks

Oral hypoglycemic drugs, including acetohexamide, have been associated with increased cardiovascular mortality. Talk to your doctor about the possible risks, benefits, and alternatives of using this drug for your condition.[2]

References

  1. ^ [1] - Metformin Side Effects
  2. ^ Medline Plus - Acetohexamide


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