Adverts

Open Access Articles- Top Results for Acetylornithine deacetylase

Acetylornithine deacetylase

acetylornithine deacetylase
Identifiers
EC number 3.5.1.16
CAS number 9025-12-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, an acetylornithine deacetylase (EC 3.5.1.16) is an enzyme that catalyzes the chemical reaction

N2-acetyl-L-ornithine + H2O <math>\rightleftharpoons</math> acetate + L-ornithine

Thus, the two substrates of this enzyme are N2-acetyl-L-ornithine and H2O, whereas its two products are acetate and L-ornithine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N2-acetyl-L-ornithine amidohydrolase. Other names in common use include acetylornithinase, N-acetylornithinase, and 2-N-acetyl-L-ornithine amidohydrolase. This enzyme participates in urea cycle and metabolism of amino groups.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2F7V and 2F8H.

References

Lua error in package.lua at line 80: module 'Module:Buffer' not found.