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Adapalene/benzoyl peroxide

Adapalene/benzoyl peroxide
Combination of
Adapalene Retinoid
Benzoyl peroxide Peroxide
Clinical data
Trade names Epiduo
  • US: C (Risk not ruled out)
  • (Prescription only)
D10AD03, D10AE51
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Adapalene/benzoyl peroxide is a prescription drug combination for the treatment of acne, marketed by Galderma under the trade name Epiduo.[1] Its trade name in Canada is TactuPump, where it was previously known as Tactuo.[2]

It consists of a combination of adapalene (0.1%) and benzoyl peroxide (2.5%) in a topical gel formulation.[1] This preparation does not create any bacterial resistance during long-term application as it does not contain an antibiotic.


Patients are advised to exercise caution in using Epiduo together with other skin products containing sulfur, resorcinol, or salicylic acid, or with medicated or abrasive dirts and cleansers.[3] Skin products with high levels of alcohol or astringents should also be avoided.[3] Using topical products with a strong drying effect in combination with Epiduo can increase irritation.[3]

Side effects

Commonly reported side effects include the following:[3]


Patients are advised to avoid exposure to sunlight and sunlamps, and use sunscreen when these cannot be avoided.[3]


  1. ^ a b "FDA OKs New Acne Gel Epiduo". Retrieved 2012-01-25. 
  2. ^
  3. ^ a b c d e "Full prescribing information" (PDF). Retrieved 2012-01-25. 

External links

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