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Alatrofloxacin

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Alatrofloxacin
250px
Systematic (IUPAC) name
7-[(1R,5S)-6-{[(2S)-1-{[(2S)-2-Aminopropanoyl]amino}-1-oxopropan-2-yl]amino}-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
MedlinePlus a605016
  • US: C (Risk not ruled out)
  • Withdrawn
Intravenous
Pharmacokinetic data
Bioavailability N/A
Protein binding 76% (trovafloxacin)
Metabolism Quickly hydrolyzed to trovafloxacin
Half-life 9 to 12 hours (trovafloxacin)
Excretion Fecal and renal (trovafloxacin)
Identifiers
146961-76-4 7pxN
None
ChemSpider 21243647 7pxN
UNII 7QVV6I50DT 7pxY
ChEMBL CHEMBL1201197 7pxN
Chemical data
Formula C26H25F3N6O5
558.509 g/mol
 14pxN (what is this?)  (verify)

Alatrofloxacin (Trovan IV) is a fluoroquinolone antibiotic developed by Pfizer, delivered as a mesylate salt.[1]

Trovafloxacin and alatrofloxacin were both withdrawn from the U.S. market in 2001.

See also

References

  1. "Center for Drug Evaluation and Research – Application Number: 020759/020760 – Chemistry Review(s)" (PDF). Food and Drug Administration. Retrieved 29 August 2014. 


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