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Open Access Articles- Top Results for Aldolase C

Aldolase C

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Identifiers
SymbolsALDOC ; ALDC
External IDsOMIM103870 MGI101863 HomoloGene21073 GeneCards: ALDOC Gene
EC number4.1.2.13
RNA expression pattern
File:PBB GE ALDOC 202022 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez23011676
EnsemblENSG00000109107ENSMUSG00000017390
UniProtP09972P05063
RefSeq (mRNA)NM_005165NM_009657
RefSeq (protein)NP_005156NP_033787
Location (UCSC)Chr 17:
26.9 – 26.9 Mb
Chr 11:
78.32 – 78.33 Mb
PubMed search[1][2]

Aldolase C, fructose-bisphosphate, also known as ALDOC, is an enzyme that, in humans, is encoded by the ALDOC gene.[1][2]

Function

This gene encodes a member of the class I fructose-bisphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose 1,6-bisphosphate and fructose-1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde 3-phosphate or glyceraldehyde, respectively.[1]

Interactive pathway map

Template:GlycolysisGluconeogenesis WP534

References

  1. ^ a b "Entrez Gene: ALDOC aldolase C, fructose-bisphosphate". 
  2. ^ Rocchi M, Vitale E, Covone A, Romeo G, Santamaria R, Buono P, Paolella G, Salvatore F (June 1989). "Assignment of human aldolase C gene to chromosome 17, region cen----q21.1". Hum. Genet. 82 (3): 279–82. PMID 2731939. doi:10.1007/BF00291170. 

Further reading

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