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Open Access Articles- Top Results for Aleglitazar

Aleglitazar

Aleglitazar
200px
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IUPAC name
(2S)-2-methoxy-3-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-7-benzothiophenyl]propanoic acid
Other names
Ro-0728804, R-1439
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475479-34-6 7pxN
ChEMBL ChEMBL519504 7pxY
ChemSpider 8450255 7pxY
DrugBank DB08483 7pxY
Jmol-3D images Image
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KEGG D08845 7pxY
PubChem Template:Chembox PubChem/format
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C24H23NO5S
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Aleglitazar is a peroxisome proliferator-activated receptor agonist (hence a PPAR modulator ) with affinity to PPARα and PPARγ, which was under development by Hoffmann–La Roche for the treatment of type II diabetes.[1] It is no longer in phase III clinical trials.[2]

References

  1. ^ "Statement on a nonproprietary name adopted by the USAN Council: Aleglitazar" (PDF). United States Adopted Names. American Medical Association. Retrieved 2008-08-17. 
  2. ^ "Roche halts diabetes drug trial in blow to pipeline". Roche. Retrieved 2013-07-10. 


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