Open Access Articles- Top Results for Alimemazine


File:Alimemazine Tartrate 10mg.jpg
Systematic (IUPAC) name
Clinical data
AHFS/ International Drug Names
  • AU: C
Pharmacokinetic data
Metabolism Hepatic
Half-life 4.78 ± 0.59 hours[1]
84-96-8 7pxY
PubChem CID 5574
DrugBank DB01246 7pxY
ChemSpider 5373 7pxY
UNII 76H78MJJ52 7pxY
KEGG D07125 7pxY
Chemical data
Formula C18H22N2S
298.447 g/mol
 14pxY (what is this?)  (verify)

Alimemazine (INN), also known as trimeprazine (USAN and former BAN); brand names Nedeltran, Panectyl, Repeltin, Therafene, Theraligene, Theralen, Theralene, Vallergan, Vanectyl, and Temaril), commonly provided as a tartrate salt, is a phenothiazine derivative that is used as an antipruritic (it prevents itching from causes such as eczema or poison ivy, by acting as an antihistamine).[2] It also acts as a sedative, hypnotic, and antiemetic for prevention of motion sickness. Although it is structurally related to drugs such as chlorpromazine, it is not used as an antipsychotic.[3] In the Russian Federation, it is marketed under the brand name Teraligen for the treatment of anxiety disorders (including GAD), organic mood disorders, sleep disturbances, personality disorders accompanied by asthenia and depression, somatoform autonomic dysfunction and various neuroses.[4]

Alimemazine is not approved for use in humans in the United States. The combination of alimemazine and prednisolone (commonly sold under the brand name Temaril-P is licensed as an antipruritic and antitussive in dogs.


  1. ^ Hu OY, Gfeller E, Perrin JH, Curry SH (March 1986). "Relative bioavailability of trimeprazine tablets investigated in man using HPLC with electrochemical detection". The Journal of Pharmacy and Pharmacology 38 (3): 172–6. PMID 2871150. doi:10.1111/j.2042-7158.1986.tb04539.x. 
  2. ^ "PubChem CID 78032". 
  3. ^ "Drugbank:Trimeprazine". 
  4. ^ "Russian Register of Medicines: “Teraligen” film-coated tablets (alimemazine tartrate) Patient Information Leaflet (in Russian). Revised September 2013.". 

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