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Alizapride

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Alizapride
File:Alizapride.svg
File:3D Alizapride.png
Systematic (IUPAC) name
N-[(1-allylpyrrolidin-2-yl)methyl]-6-methoxy-1H-benzo[d][1,2,3]triazole-5-carboxamide
Clinical data
AHFS/Drugs.com International Drug Names
  • (Prescription only)
Oral, IM, IV
Pharmacokinetic data
Half-life 3 hours
Excretion Renal
Identifiers
59338-93-1 7pxY
A03FA05
PubChem CID 43008
DrugBank DB01425 7pxY
ChemSpider 39202 7pxY
UNII P55703ZRZY 7pxY
KEGG D07102 7pxY
ChEMBL CHEMBL290194 7pxY
Chemical data
Formula C16H21N5O2
315.37 g/mol
 14pxY (what is this?)  (verify)

Alizapride (Litican, Plitican, Superan, Vergentan) is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. It is structurally related to metoclopramide and other benzamides.[1]

See also

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Anon., Drugs Future 1981, 6, 11.

References

  1. ^ Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M (1988). "Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial". Cancer Chemother Pharmacol 22 (4): 316–20. PMID 3048762. doi:10.1007/bf00254238. 



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