Open Access Articles- Top Results for Alopecia totalis

Alopecia totalis

Alopecia totalis
A woman with alopecia totalis.
Classification and external resources
ICD-10 L63.0
NCI Alopecia totalis
Patient UK Alopecia totalis

Alopecia totalis is the loss of all head hair. Its causes are unclear, but believed to be autoimmune. Stress is thought to be a contributor in alopecia areata. However, many with the disorder lead relatively low stress lives.


Methotrexate and corticosteroids are proposed treatments.[1]

Scalp cooling has specifically been used to prevent alopecia in docetaxel chemotherapy,[2] although it has been found prophylactic in other regimens as well.[3][4][5] Treatment effects may take time to resolve, with one study showing breast cancer survivors wearing wigs up to 2 years after chemotherapy.[6]

See also


  1. ^ Joly, Pascal (2006). "The use of methtrexate alone or in combination with low doses of oral corticosteroids in the treatment of alopecia totalis or universalis". Journal of the American Academy of Dermatology 55 (4): 632–6. PMID 17010743. doi:10.1016/j.jaad.2005.09.010. 
  2. ^ Hurk, C. J. G.; Breed, W. P. M.; Nortier, J. W. R. (2012). "Short post-infusion scalp cooling time in the prevention of docetaxel-induced alopecia". Supportive Care in Cancer 20 (12): 3255–3260. PMID 22539051. doi:10.1007/s00520-012-1465-0.  edit
  3. ^ Lemieux, J. (2012). "Reducing chemotherapy-induced alopecia with scalp cooling". Clinical advances in hematology & oncology : H&O 10 (10): 681–682. PMID 23187775.  edit
  4. ^ Van Den Hurk, C. J.; Peerbooms, M.; Van De Poll-Franse, L. V.; Nortier, J. W.; Coebergh, J. W. W.; Breed, W. P. (2012). "Scalp cooling for hair preservation and associated characteristics in 1411 chemotherapy patients - Results of the Dutch Scalp Cooling Registry". Acta Oncologica 51 (4): 497–504. PMID 22304489. doi:10.3109/0284186X.2012.658966.  edit
  5. ^ Yeager, C. E.; Olsen, E. A. (2011). "Treatment of chemotherapy-induced alopecia". Dermatologic Therapy 24 (4): 432–442. PMID 21910801. doi:10.1111/j.1529-8019.2011.01430.x.  edit
  6. ^ Oshima, Y.; Watanabe, T.; Nakagawa, S.; Endo, A.; Shiga, C. (2012). "A questionnaire survey about hair loss after chemotherapy for breast cancer". Gan to kagaku ryoho. Cancer & chemotherapy 39 (9): 1375–1378. PMID 22996772.  edit

External links

Lua error in package.lua at line 80: module 'Module:Buffer' not found.