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Open Access Articles- Top Results for Alpha-Aminobutyric acid

alpha-Aminobutyric acid

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α-Aminobutyric acid
Skeletal formula of α-aminobutanoic acid
Ball-and-stick model of the α-aminobutanoic acid molecule as a zwitterion
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IUPAC name
2-Aminobutanoic acid
Other names
2-Aminobutyric acid; α-Aminobutanoic acid; Ethylglycine
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2835-81-6 7pxY
ChEBI CHEBI:35621 7pxY
ChEMBL ChEMBL55242 7pxY
ChemSpider 6405 7pxY
Jmol-3D images Image
PubChem Template:Chembox PubChem/format
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C4H9NO2
Molar mass 103.12 g/mol
Acidity (pKa) 2.55 (carboxyl), 9.60 (amino)[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 14pxY verify (what is10pxY/10pxN?)
Infobox references

α-Aminobutyric acid (AABA), also known as homoalanine in biochemistry, is a non-proteinogenic alpha amino acid with chemical formula C4H9NO2. The straight two carbon side chain is one carbon longer than alanine, hence the prefix homo-.

Homoalaine is biosynthesised by transaminating oxobutyrate, a metabolite in isoleucine biosynthesis. It is used by nonribosomal peptide synthases. One example of a nonribosomal peptide containing homoalanine is ophthalmic acid, which was first isolated from calf lens.

α-Aminobutyric acid is an isomer of the amino acid aminobutyric acid. It has two other isomers, γ-aminobutyric acid (GABA) and β-aminobutyric acid (BABA).

In contrast, GABA is a neurotransmitter and is not used in protein synthesis, and it is almost always referred to as "GABA".

References

  1. ^ Dawson, R.M.C., et al., Data for Biochemical Research, Oxford, Clarendon Press, 1959.


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