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Open Access Articles- Top Results for Alphenal

Alphenal

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Alphenal
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Systematic (IUPAC) name
5-phenyl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
Clinical data
  • US: Rx-only, Schedule III
Oral
Identifiers
115-43-5 7pxY
None
PubChem CID 8274
ChemSpider 7975 7pxY
UNII 7T7L08Q9JI 7pxY
Synonyms 5-Phenyl-5-allylbarbituric acid
Chemical data
Formula C13H12N2O3
244.246 g/mol
 14pxY (what is this?)  (verify)

Alphenal (Alphenal, Efrodal, Prophenal, Sanudorm), also known as 5-allyl-5-phenylbarbituric acid, is a barbiturate derivative developed in the 1920s.[1] It has primarily anticonvulsant properties, and was used occasionally for the treatment of epilepsy or convulsions, although not as commonly as better known barbiturates such as phenobarbital.[2][3] [4][5]

LD50: Mouse (Oral): 280 mg/kg

References

  1. DE Patent 526854
  2. Carissimi M, Nuovi Barbiturici Alogenati. Farmaco. Ediozione scientifica. 17(6):390-413. (1962).
  3. Martin, J. R.; Godel, T.; Hunkeler, W.; Jenck, F.; Moreau, J.-L.; Sleight, A. J.; Widmer, U. (2000). "Psychopharmacological Agents". doi:10.1002/0471238961.1619250313011820.a01. 
  4. Hans Brandenberger; Robert A. A. Maes (1997). Analytical Toxicology: For Clinical, Forensic, and Pharmaceutical Chemists. Walter de Gruyter. p. 348. ISBN 978-3-11-010731-9. Retrieved 19 May 2012. 
  5. Pelayo Camps García; Santiago Vázquez Cruz; Carmen Escolano Mirón (28 January 2005). Fundamentos de síntesis de fármacos. Edicions Universitat Barcelona. p. 161. ISBN 978-84-475-2876-9. Retrieved 19 May 2012. 



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