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Alprenolol

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Alprenolol
File:Alprenolol2.svg
Systematic (IUPAC) name
(RS)-1-(2-allylphenoxy)-3-(isopropylamino)propan-2-ol
Clinical data
AHFS/Drugs.com International Drug Names
Oral
Pharmacokinetic data
Protein binding 80% - 90%
Half-life 2-3 hours → 4-OH-alprenolol
Identifiers
13655-52-2 7pxY
C07AA01
PubChem CID 2119
IUPHAR ligand 563
DrugBank DB00866 7pxY
ChemSpider 2035 7pxY
UNII 877K5MQ27W 7pxY
KEGG D07156 7pxY
ChEBI CHEBI:51211 7pxY
ChEMBL CHEMBL266195 7pxY
Chemical data
Formula C15H23NO2
249.34 g/mol
 14pxY (what is this?)  (verify)

Alprenolol, or alfeprol, alpheprol, and alprenololum (Gubernal, Regletin, Yobir, Apllobal, Aptine, Aptol Duriles), is a non-selective beta blocker as well as 5-HT1A receptor antagonist, used in the treatment of angina pectoris.[1] It is no longer marketed by AstraZeneca, but may still be available from other pharmaceutical companies or generically.

References

  1. ^ Hickie JB (August 1970). "Alprenolol ("aptin") in angina pectoris. A double-blind multicentre trial". Med. J. Aust. 2 (6): 268–72. PMID 4393977. 

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