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Amanullinic acid

Amanullinic acid
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Other names
1-L-Aspartic acid-3-isoleucine-alpha-amanitin
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54532-45-5 7pxY
ChemSpider 149798 7pxY
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PubChem Template:Chembox PubChem/format
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C39H53N9O13S
Molar mass 887.96 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Amanullinic acid is a cyclic nonribosomal peptide. It is an amatoxin, all of which are found in several members of the Amanita genus of mushrooms. The oral LD50 of amanullinic acid is approximately 0.1 mg/kg in mice.[1]

Toxicology

Like other amatoxins, amanullinic acid is an inhibitor of RNA polymerase II.

See also

References

  1. ^ T. Wieland and Faulstich H. (1978). "Amatoxins, Phallotoxins, Phallolysin, and Antamanide: the Biologically Active Components of Poisonous Amanita Mushrooms". CRC Critical Reviews in Biochemistry 5 (3): 185–260. PMID 363352. doi:10.3109/10409237809149870. 

External links