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Open Access Articles- Top Results for Aminoacetonitrile

Aminoacetonitrile

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Aminoacetonitrile

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IUPAC name
2-Aminoacetonitrile[1]
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540-61-4 7pxY ChemSpider 10439 7pxY EC number 208-751-8 Jmol-3D images Image MeSH Aminoacetonitrile PubChem Template:Chembox PubChem/format RTECS number AL7750000 Template:Chembox UNII colspan=2 style="background:#f8eaba; border-top:2px solid transparent; border-bottom:2px solid transparent; text-align:center;" #REDIRECTmw:Help:Magic words#Other
This page is a soft redirect. Properties

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GHS pictograms The exclamation-mark pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) The health hazard pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) GHS signal word WARNING H302, H312, H332, H351 P280 EU classification Harmful Xn R-phrases R20/21/22, R40 S-phrases S36 colspan=2 style="background:#f8eaba; border-top:2px solid transparent; border-bottom:2px solid transparent; text-align:center;" #REDIRECTmw:Help:Magic words#Other
This page is a soft redirect. Related compounds

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Related alkanenitriles
Related compounds
DBNPA
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Aminoacetonitrile is a simple organic compound containing both nitrile and amino groups. It is somewhat similar to the simplest amino acid, glycine. This compound is commercially available as the chloride and sulfate salts.

Production and applications

Industrially aminoacetonitrile is produced from glycolonitrile by reaction with ammonia:

HOCH2CN + NH3 → H2NCH2CN + H2O

The aminoacetonitrile can be hydrolysed to give glycine:[2]

Aminoacetonitrile derivatives are useful anthelmintics. They act as nematode specific ACh agonists[3] causing a spastic paralysis and rapid expulsion from the host.

Occurrent in the interstellar medium

In 2008, aminoacetonitrile was discovered in the Large Molecule Heimat, a giant gas cloud near the galactic center in the constellation Sagittarius by the Max Planck Institute for Radio Astronomy.[4] This discovery is significant to the debate on whether glycine exists widely in the universe.

External links

Property data at the National Institute of Standards and Technology NIST

References

  1. ^ "Aminoacetonitrile - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 27 March 2005. Identification. Retrieved 5 June 2012. 
  2. ^ Peter Pollak, Gérard Romeder, Ferdinand Hagedorn, Heinz-Peter Gelbke "Nitriles" Ullmann's Encyclopedia of Industrial Chemistry 2002, Wiley-VCH, Weinheim. doi:10.1002/14356007.a17_363
  3. ^ Kaminsky, R.; Ducray, P.; Jung, M.; Clover, R.; Rufener, L.; Bouvier, J.; Weber, S. S.; Wenger, A.; Wieland-Berghausen, S. et al. (2008). "A new class of anthelmintics effective against drug-resistant nematodes". Nature 452 (7184): 176–180. Bibcode:2008Natur.452..176K. PMID 18337814. doi:10.1038/nature06722. 
  4. ^ Belloche, A.; Menten, K. M.; Comito, C.; Müller, H. S. P.; Schilke, P.; Ott, J.; Thorwirth, S.; Hieret, C. (2008). "Detection of amino acetonitrile in Sgr B2(N)" (PDF). Astronomy and Astrophysics 482 (1): 179–196. Bibcode:2008A&A...482..179B. arXiv:0801.3219. doi:10.1051/0004-6361:20079203. 

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