Open Access Articles- Top Results for Aortitis


Classification and external resources
ICD-10 I77.6
ICD-9 447.6
eMedicine med/158
NCI Aortitis
Patient UK Aortitis
MeSH D001025

Aortitis is the inflammation of the aortic wall. The disorder is potentially life-threatening and rare. It is reported that there are only 1-3 new cases of aortitis per year per million people in the United States and Europe.[1] Aortitis is found in a wide range of ages spanning from 10 to 40 years of age.[1]


This inflammation has a number of possible causes, including trauma, viral infection, certain immune disorders, and bacterial infection (notably, syphilis).[1]

Causes are associated with infections or immune and connective tissue disorders. Aortitis is most commonly seen in patients with syphilis, autoimmune vasculitis, giant cell arteritis, Takayasu's arteritis, and rheumatoid arthritis.[2] There is a wide range of symptoms that are dependent on the location of the aortic inflammation or associated disorder. A few symptoms recognized in patients are fever, chills, muscle pains, and malaise (general discomfort).[2] In addition, hypertension (high blood pressure) may occur. Hypertension happens when the renal artery narrows and elasticity of the aorta and branches decrease.[3]


Management appears to include the following treatment priorities; stop the inflammation, treat complications, prevent and monitor for re-occurrence.


If untreated, has three distinct phases.[1] The first is a prepulseless inflammatory stage with nonspecific symptoms such as fatigue, arthralgias, and low-grade fevers. Phase two includes vascular inflammation with pain secondary to the condition, along with tenderness to palpation over the site. The last phase includes symptoms of ischemia and pain associated with the use of limbs. Limbs are also cool and clammy in this stage.


  1. ^ a b c d "eMedicine - Aortitis : Article by Masato Okada, MD, FACP, FACR, FAAAAI". Archived from the original on 14 July 2007. Retrieved 2007-07-28. 
  2. ^ a b [Taber's Cyclopedic Medical Dictionary. 19th ed. Philadelphia: F.A. Davis, 2001.]
  3. ^ Link text, American Heart Association.