Open Access Articles- Top Results for Aortoiliac occlusive disease

Aortoiliac occlusive disease

Aortoiliac occlusive disease
Plate from Gray's Anatomy showing the abdominal aorta and the common iliac arteries.
Classification and external resources
ICD-9 444.0
DiseasesDB 29335
eMedicine med/2759
NCI Aortoiliac occlusive disease
Patient UK Aortoiliac occlusive disease
MeSH D007925
File:Leriche's syndrome.jpg
Leriche's syndrome (X-ray)

In medicine, aortoiliac occlusive disease, also known as Leriche's syndrome and Leriche syndrome, is a form of peripheral artery disease involving the bifurcation of the abdominal aorta as it transitions into the common iliac arteries.

Signs and symptoms

Classically, it is described in male patients as a triad of the following signs and symptoms:

  1. claudication of the buttocks and thighs
  2. absent or decreased femoral pulses
  3. impotence

This combination is known as Leriche syndrome.[1] However, any number of symptoms may present, depending on the distribution and severity of the disease, such as muscle atrophy, slow wound healing in the legs, and critical limb ischemia.


Treatment involves revascularization typically using either angioplasty or a type of vascular bypass


The condition was first described by Robert GrahamTemplate:Disambiguation needed in 1814, but the condition with its triad of symptoms was ascribed to René Leriche.[4] Leriche, a French surgeon, linked the pathophysiology with the anatomy of the condition. John Hunter's dissections of atherosclerotic aortic bifurcations from the late 18th century are preserved at the Hunterian Museum, but Leriche was first to publish on the subject based on a patient he treated with the condition at the age of 30. Following treatment the 30 year old was able to walk without pain and maintain an erection.[citation needed]

See also


  1. ^ [1]
  2. ^ Lee BY, Guerra J (1994). "Axillofemoral bypass graft in a spinal cord injured patient with impending gangrene". The Journal of the American Paraplegia Society 17 (4): 171–6. PMID 7869060. 
  3. ^ McKinsey JF (1995). "Extra-anatomic reconstruction". Surg. Clin. North Am. 75 (4): 731–40. PMID 7638717. 
  4. ^ synd/2747 at Who Named It?

External links