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Open Access Articles- Top Results for Aprobarbital

Aprobarbital

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Aprobarbital
File:Aprobarbital Structural Formulae.svg
File:Aprobarbital ball-and-stick animation.gif
Systematic (IUPAC) name
5-propan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
Identifiers
77-02-1 7pxY
N05CA05
PubChem CID 6464
DrugBank DB01352 7pxY
ChemSpider 6221 7pxY
UNII Q0YKG9L6RF 7pxY
KEGG D00698 7pxY
ChEBI CHEBI:2791 7pxY
ChEMBL CHEMBL7863 7pxY
Synonyms aprobarbital, Oramon, allylpropymal, Alurate, 5-isopropyl- 5-allylbarbituric acid
Chemical data
Formula C10H14N2O3
210.23 g/mol
 14pxY (what is this?)  (verify)

Aprobarbital (as known in the United States, or aprobarbitone (as known elsewhere), sold as Oramon, Somnifaine, and Allonal, is a barbiturate derivative invented in the 1920s by Ernst Preiswerk. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia.[1] Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed as it has been replaced by newer drugs with a better safety margin.

References

  1. ^ Reddemann H, Turk E. Oramon poisoning in infancy and childhood. Observations on 12 aprobarbital poisonings (German). Das Deutsche Gesundheitswesen. 1966 May 12;21(19):878-81.


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