Open Access Articles- Top Results for Aquaporin 3

Aquaporin 3

SymbolsAQP3 ; AQP-3; GIL
External IDsOMIM600170 MGI1333777 HomoloGene21025 IUPHAR: 690 GeneCards: AQP3 Gene
RefSeq (mRNA)NM_004925NM_016689
RefSeq (protein)NP_004916NP_057898
Location (UCSC)Chr 9:
33.44 – 33.45 Mb
Chr 4:
41.09 – 41.1 Mb
PubMed search[1][2]

Aquaporin 3 is found in the basolateral cell membrane of principal collecting duct cells and provide a pathway for water to exit these cells.[1] In the kidney, AQP3 gene expression is not regulated by vasopressin (ADH).[2] This protein is also a determinant for the GIL blood group system.[3]

See also


  1. ^ Sasaki S, Ishibashi K, Marumo F (1998). "Aquaporin-2 and -3: representatives of two subgroups of the aquaporin family colocalized in the kidney collecting duct". Annu. Rev. Physiol. 60: 199–220. PMID 9558461. doi:10.1146/annurev.physiol.60.1.199. 
  2. ^ Dibas AI, Mia AJ, Yorio T (1998). "Aquaporins (water channels): role in vasopressin-activated water transport". Proc. Soc. Exp. Biol. Med. 219 (3): 183–99. PMID 9824541. doi:10.3181/00379727-219-44332. 
  3. ^ Roudier N, Ripoche P, Gane P, Le Pennec PY, Daniels G, Cartron JP, Bailly P (2002). "AQP3 deficiency in humans and the molecular basis of a novel blood group system, GIL". J. Biol. Chem. 277 (48): 45854–9. PMID 12239222. doi:10.1074/jbc.M208999200. 

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