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Open Access Articles- Top Results for Astressin-B

Astressin-B

Astressin-B (AST) is a nonselective corticotropin releasing hormone antagonist that reduces the synthesis of ACTH and cortisol.[1]

Reducing ACTH synthesis, it improves the sexual drive of rats under stressing conditions.[2]

In 2011, research showed that treatment with astressin-B caused the sudden growth of hair in mice bred for a propensity for stress.[3][4]

References

  1. ^ Vulliémoz NR, Xiao E, Xia-Zhang L, Rivier J, Ferin M (March 2008). "Astressin B, a nonselective corticotropin-releasing hormone receptor antagonist, prevents the inhibitory effect of ghrelin on luteinizing hormone pulse frequency in the ovariectomized rhesus monkey". Endocrinology 149 (3): 869–74. PMC 2275354. PMID 18063681. doi:10.1210/en.2007-1350. 
  2. ^ Miwa Y, Nagase K, Oyama N, Akino H, Yokoyama O (March 2011). "Effect of corticotropin-releasing factor receptor antagonist on psychologically suppressed masculine sexual behavior in rats". J Sex Med 8 (3): 688–95. PMID 20946165. doi:10.1111/j.1743-6109.2010.02055.x. 
  3. ^ Rebecca Boyle (2011-02-16). "Researching Stress, Scientists May Have Accidentally Found Baldness Cure". popsci.com. 
  4. ^ Wang, L.; Million, M.; Rivier, J.; Rivier, C.; Craft, N.; Stenzel-Poore, M. P.; Taché, Y. (2011). Polymenis, Michael, ed. "CRF Receptor Antagonist Astressin-B Reverses and Prevents Alopecia in CRF Over-Expressing Mice". PLoS ONE 6: e16377. doi:10.1371/journal.pone.0016377.  edit


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