Open Access Articles- Top Results for Autoinjector


A variety of autoinjectors in use with the US Armed Forces

An autoinjector (or auto-injector) is a medical device designed to deliver a single dose of a particular (typically life-saving) drug.

Most autoinjectors are spring-loaded syringes. By design, autoinjectors are easy to use and are intended for self-administration by patients, or administration by untrained personnel. The site of injection depends on the drug loaded, but it typically is administered into the thigh or the buttocks. The injectors were initially designed to overcome the hesitation associated with self-administration of the needle-based drug delivery device.


File:Components of a Adalimumab-Humira pen - annotated.jpg
Components of a Humira autoinjector pen. See file details for detailed explanation of components.

The autoinjector keeps the needle tip shielded prior to injection and also has a passive safety mechanism to prevent accidental firing (injection). Injection depth can be adjustable or fixed and a function for needle shield removal may be incorporated. Just by pressing a button, the syringe needle is automatically inserted and the drug is delivered. Once the injection is completed some auto injectors have visual indication to confirm that the full dose has been delivered. Autoinjectors contain glass syringes, this can make them fragile and contamination can occur. More recently, companies have been looking into making autoinjectors syringes out of plastic to prevent this issue.


Military use


A newer variant of the autoinjector is the gas jet autoinjector, which contains a cylinder of pressurised gas and propels a fine jet of liquid through the skin without the use of a needle. This has the advantage that the autoinjector can be reloaded, and a variety of different doses or different drugs can be used, although the only widespread application to date has been for the administration of insulin in the treatment of diabetes.[1][2]

See also


  1. ^ "1". 2001-01-16. Retrieved 2010-07-07. 
  2. ^ 2[dead link]

External links