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Open Access Articles- Top Results for Azelnidipine

Azelnidipine

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Azelnidipine
File:Azelnidipine.png
Systematic (IUPAC) name
O3-[1-[di(phenyl)methyl]azetidin-3-yl] O5-propan-2-yl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Clinical data
AHFS/Drugs.com International Drug Names
  • (Prescription only)
Oral
Identifiers
123524-52-7 7pxN
None
PubChem CID 65948
ChemSpider 59352 7pxY
UNII PV23P19YUG 7pxY
KEGG D01145 7pxY
ChEMBL CHEMBL1275868 7pxN
Chemical data
Formula C33H34N4O6
582.64 g/mol
 14pxN (what is this?)  (verify)

Azelnidipine (INN; marketed under the brand name Calblock) is a dihydropyridine calcium channel blocker. It is sold in Japan by Daiichi-Sankyo pharmaceuticals, Inc. Unlike nicardipine, it has a gradual onset and has a long-lasting hypotensive effect, with little increase in heart rate.[1]

References

  1. ^ Oizumi K, Nishino H, Koike H, Sada T, Miyamoto M, Kimura T (September 1989). "Antihypertensive effects of CS-905, a novel dihydropyridine Ca++ channel blocker". Jpn. J. Pharmacol. 51 (1): 57–64. PMID 2810942. doi:10.1254/jjp.51.57. Scholar search[dead link]

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