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Open Access Articles- Top Results for BHFF

BHFF

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BHFF
File:BHFF structure.png
Systematic (IUPAC) name
5,7-Bis(1,1-dimethylethyl)-3-hydroxy-3(trifluoromethyl)-2(3H)-benzofuranone
Clinical data
Identifiers
123557-91-5 7pxY
PubChem CID 4332683
ChemSpider 3537035 7pxY
Chemical data
Formula C17H21F3O3
330.341 g/mol
 14pxY (what is this?)  (verify)

BHFF is a compound used in scientific research which acts as a positive allosteric modulator at the GABAB receptor. It has anxiolytic effects in animal studies, and good oral bioavailability.[1]

References

  1. ^ Malherbe, P; Masciadri, R; Norcross, RD; Knoflach, F; Kratzeisen, C; Zenner, MT; Kolb, Y; Marcuz, A; Huwyler, J (2008). "Characterization of (R,S)-5,7-di-tert-butyl-3-hydroxy-3-trifluoromethyl-3H-benzofuran-2-one as a positive allosteric modulator of GABAB receptors". British Journal of Pharmacology 154 (4): 797–811. PMC 2439845. PMID 18536733. doi:10.1038/bjp.2008.135. 



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