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BST1

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Identifiers
SymbolsBST1 ; CD157
External IDsOMIM600387 MGI105370 HomoloGene3198 GeneCards: BST1 Gene
EC number3.2.2.6
RNA expression pattern
File:PBB GE BST1 205715 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez68312182
EnsemblENSG00000109743ENSMUSG00000029082
UniProtQ10588Q64277
RefSeq (mRNA)NM_004334NM_009763
RefSeq (protein)NP_004325NP_033893
Location (UCSC)Chr 4:
15.7 – 15.74 Mb
Chr 5:
43.82 – 43.84 Mb
PubMed search[1][2]

ADP-ribosyl cyclase 2 is an enzyme that in humans is encoded by the BST1 gene.[1][2]

Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.[2]

See also

References

  1. ^ Kaisho T, Ishikawa J, Oritani K, Inazawa J, Tomizawa H, Muraoka O, Ochi T, Hirano T (Jul 1994). "BST-1, a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth". Proc Natl Acad Sci U S A 91 (12): 5325–9. PMC 43987. PMID 8202488. doi:10.1073/pnas.91.12.5325. 
  2. ^ a b "Entrez Gene: BST1 bone marrow stromal cell antigen 1". 

Further reading

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