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Basic research (also called pure research, fundamental research, and discovery research) is a systematic study directed toward greater knowledge or understanding of the fundamental aspects of phenomena. Basic research is executed without thought of a practical end goal, without specific applications or products in mind.
Basic research has been described as arising out of curiosity. Basic research is contrasted with applied research, which is research focused on a particular problem or application. Basic research lays the foundation for advancements in knowledge that lead to applied gains later on, occasionally as a result of unexpected discoveries.
The International Council for Science, in a December 2004 position statement, urged support for and adequate public investment in basic research, stating that basic science, innovation, and development are intertwined.
In the United States, pure research is mainly carried out by universities and institutes financed by the government.  However, in the 2010s, as appropriations for government research have decreased or remained stagnate, funding by wealthy entrepreneurs has emerged as a significant source of support.
Basic research advances fundamental knowledge about the world. It focuses on refuting or supporting theories that explain observed phenomena. Pure research is the source of most new scientific ideas and ways of thinking about the world. It can be exploratory, descriptive, or explanatory; however, explanatory research is the most common.
Basic research generates new ideas, principles, and theories, which may not be immediately utilized but nonetheless form the basis of progress and development in different fields. Today's computers, for example, could not exist without research in pure mathematics conducted over a century ago, for which there was no known practical application at the time. Basic research rarely helps practitioners directly with their everyday concerns; nevertheless, it stimulates new ways of thinking that have the potential to revolutionize and dramatically improve how practitioners deal with a problem in the future.
Basic versus applied science
Applied science focuses on the development of technology and techniques. In contrast, basic science develops scientific knowledge and predictions, principally in natural sciences but also in other empirical sciences, which are used as the scientific foundation for applied science. Basic science develops and establishes information to predict phenomena and perhaps to understand nature, whereas applied science uses portions of basic science to develop interventions via technology or technique to alter events or outcomes. Applied and basic sciences can interface closely in research and development.
A distinction can be made between basic science and disciplines such as medicine and technology. They can be grouped as STM (science, technology & medicine) or STS (science, technology & society). These groups are interrelated and influence each other, although they may differ in the specifics such as methods and standards.
"Basic science" or "fundamental science" may also refer to physics. In philosophy of science, the branches of science are often described such that fundamental physics is the foundation underlying the others, called special sciences, that rest upon and in principle are derivable from and reducible to fundamental physics. In a conceived unity of science, the special sciences investigate domains whose entities and laws emerge from the domain of the idealized fundamental physics. Basic science may also be used to refer to the natural sciences in general, as compared to the social sciences and applied sciences.
Whereas fundamental physics seeks laws of universal regularity, special sciences usually include ceteris paribus laws, predictively accurate to high probability in "normal conditions" or with "all else equal", but having exceptions. Although exceptionless, chemistry's laws were presumably reduced to fundamental physics—to quantum mechanics and then quantum electrodynamics—and so chemistry, presumed to emerge, is a special science. Bridging physical sciences to biological sciences via biochemistry, and influencing sciences generally, chemistry has been viewed as the central science.
- "What is basic research?" (PDF). National Science Foundation. Retrieved 2014-05-31.
Basic research is performed without thought of practical ends. It results in general knowledge and understanding of nature and its laws.
- Curiosity Creates Cures: The Value and Impact of Basic Research, National Institute of General Medical Sciences, National Institutes of Health.
- ICSU Position Statement: The value of basic scientific research (December 2004), International Council for Science.
- Ganapati, Priya (2008-08-27). "Bell Labs Kills Fundamental Physics Research". Wired. Archived from the original on 28 August 2008. Retrieved 2008-08-28.
- William J. Broad (March 15, 2014). "Billionaires With Big Ideas Are Privatizing American Science". The New York Times (The Times Company). Retrieved December 26, 2014.
- Research: Anyone Can Do It. By Fernando Guimaraes
- Research: Anyone Can Do It. By Fernando Guimaraes
- "Limited scope of science". & "Technology" in Bernard Davis (Mar 2000). "The scientist's world". Microbiology and Molecular Biology Reviews 64 (1): 1–12. PMC 98983. PMID 10704471. doi:10.1128/MMBR.64.1.1-12.2000.
- James McCormick (2001). "Scientific medicine—fact of fiction? The contribution of science to medicine". Occasional Paper (Royal College of General Practitioners)<span /> (80): 3–6. PMC 2560978. PMID 19790950.
- Gerard Piel, "Science and the next fifty years", § "Applied vs basic science", Bulletin of Atomic Scientists, 1954 Jan;10(1):17–20, p 18.
- Ruth-Marie E Fincher, Paul M Wallach & W Scott Richardson, "Basic science right, not basic science lite: Medical education at a crossroad", Journal of General Internal Medicine, Nov 2009;24(11):1255–58, abstract: "Thoughtful changes in education provide the opportunity to improve understanding of fundamental sciences, the process of scientific inquiry, and translation of that knowledge to clinical practice".
- Richard Smith (Mar 2006). "The trouble with medical journals". Journal of the Royal Society of Medicine 99 (3): 115–9. PMC 1383755. PMID 16508048. doi:10.1258/jrsm.99.3.115.
- Leon Eisenberg (Mar 1988). "Science in medicine: Too much or too little and too limited in scope?". American Journal of Medicine 84 (3 Pt 1): 483–91. PMID 3348249. doi:10.1016/0002-9343(88)90270-7.
- J N Clarke, S Arnold, M Everest & K Whitfield (Jan 2007). "The paradoxical reliance on allopathic medicine and positivist science among skeptical audiences". Social Science & Medicine 64 (1): 164–73. PMID 17045377. doi:10.1016/j.socscimed.2006.08.038.
- Eric Holtzman (1981). "Science, philosophy, and society: Some recent books". International Journal of Health Services 11 (1): 123–49. PMID 7016767. doi:10.2190/l5eu-e7pc-hxg6-euml.
- P M Strong PM & K McPherson (1982). "Natural science and medicine: Social science and medicine: Some methodological controversies". Social Science & Medicine 16 (6): 643–57. PMID 7089600. doi:10.1016/0277-9536(82)90454-3.
- Lucien R Karhausen (2000). "Causation: The elusive grail of epidemiology". Medicine, Health Care, and Philosophy 3 (1): 59–67. PMID 11080970. doi:10.1023/A:1009970730507.
- K Bayertz & P Nevers (1998). "Biology as technology". Clio Medica 48: 108–32. PMID 9646019.
- John V Pickstone & Michael Worboys (Mar 2011). "Focus: Between and beyond 'histories of science' and 'histories of medicine'—introduction". Isis 102 (1): 97–101. PMID 21667777. doi:10.1086/658658.
- Lester S King (May 1983). "Medicine in the USA: Historical vignettes: XI: Medicine seeks to be 'scientific'". JAMA 249 (18): 2475–9. PMID 6341631. doi:10.1001/jama.1983.03330420025028.
- Thomas Marshall (Apr 1997). "Scientific knowledge in medicine: A new clinical epistemology?". Journal of Evaluation in Clinical Practice 3 (2): 133–8. PMID 9276588. doi:10.1046/j.1365-2753.1997.00075.x.
- A Zalewski (Mar 1999). "Importance of philosophy of science to the history of medical thinking". Croatian Medical Journal 40 (1): 8–13. PMID 9933889.
- Kevork Hopayian (May 2004). "Why medicine still needs a scientific foundation: Restating the hypotheticodeductive model—part two". British Journal of General Practice 54 (502): 402–3. PMC 1266186. PMID 15372724.
- A Skurvydas (2005). "New methodology in biomedical science: Methodological errors in classical science". Medicina 41 (1): 7–16. PMID 15687745.
- Ronald A Arky (2007). "Abe Flexner, where are you? We need you!". Transactions of the American Clinical and Climatological Association 118: 89–96. PMC 1863593. PMID 18528492.
- Peter Byass (2011). "The democratic fallacy in matters of clinical opinion: Implications for analysing cause-of-death data". Emerging Themes in Epidemiology 8 (1): 1. PMC 3026021. PMID 21223568. doi:10.1186/1742-7622-8-1.
- M Brandon Westover, Kenneth D Westover KD & Matt T Bianchi (2011). "Significance testing as perverse probabilistic reasoning". BMC Medicine 9: 20. PMC 3058025. PMID 21356064. doi:10.1186/1741-7015-9-20.
- Alfredo Morabia (2005). "Epidemiological causality". History and Philosophy of the Life Sciences 27 (3-4): 365–79. PMID 16898206.
- Michael Kundi (July 2006). "Causality and the interpretation of epidemiologic evidence". Environmental Health Perspectives 114 (7): 969–74. PMC 1513293. PMID 16835045. doi:10.1289/ehp.8297.
- Andrew C Ward (2009). "The role of causal criteria in causal inferences: Bradford Hill's 'aspects of association'". Epidemiologic Perspectives & Innovations 6: 2. PMC 2706236. PMID 19534788. doi:10.1186/1742-5573-6-2.
- Gary Taubes (Mar 2001). "The soft science of dietary fat". Science 291 (5513): 2536–45. PMID 11286266. doi:10.1126/science.291.5513.2536.
- Georg W Kreutzberg (May 2005). "Scientists and the marketplace of opinions: Scientific credibility takes on a different meaning when reaching out to the public". EMBO Reports 6 (5): 393–6. PMC 1299311. PMID 15864285. doi:10.1038/sj.embor.7400405.
- John Worrall (Apr 2010). "Evidence: Philosophy of science meets medicine". Journal of Evaluation in Clinical Practice 16 (2): 356–62. PMID 20367864. doi:10.1111/j.1365-2753.2010.01400.x.
- "Medals, Awards & Prize lectures", The Royal Society website, accessed 22 Sep 2013.
- Wolfgang Spohn, The Laws of Belief: Ranking Theory and Its Philosophical Applications (Oxford: Oxford University Press, 2012), p 305.
- Alexander Reutlinger, Gerhard Schurz & Andreas Hüttemann, "Ceteris paribus laws", sec 1.1 "Systematic introduction", in Edward N Zalta, ed, The Stanford Encyclopedia of Philosophy, Spring 2011 edn.
- Vítor Neves, ch 12 "Sciences as open systems—the case of economics", in Olga Pombo, Juan M Torres, John Symons & Shahid Rahman, eds, Special Sciences and the Unity of Science (Dordrecht, Heidelberg, London, New York: Springer, 2012).
- Anita Traninger, "Emergence as a model for the study of culture", pp 67–82, in Birgit Neumann & Ansgar Nünning, eds, Travelling Concepts for the Study of Culture (Berlin & Boston: Walter de Gruyter, 2012), pp 70–71.
- Richard P Feynman, QED: The Strange Theory of Light and Matter, exp edn w/ new intro by A Zee (Princeton & London: Princeton University Press, 2006), p 5.
- "Figure 1: Contradictions lead to better theories". in Schwarz, John H (1998). "Recent developments in superstring theory". Proceedings of the National Academy of Sciences of the United States of America 95 (6): 2750–7. PMC 19640. PMID 9501161. doi:10.1073/pnas.95.6.2750.
- Theodore E Brown, H Eugene LeMay et al, Chemistry: The Central Science, 12th edn (Upper Saddle River NJ: Pearson Prentice Hall, 2012).
- Maria Burguete, ch 7 "History and philosophy of science: Towards a new epistemology", 7.3 "History of contemporary chemistry", in Maria Burguete & Liu Lam, eds, Science Matters: Humanities As Complex Systems (Singapore: World Scientific Publishing, 2008), p 139: "Considering the extent that chemical methodology has contributed to other disciplines, it is tempting to take the charge that chemistry is in danger of losing its identity, or, to turn it around and proclaim instead that chemistry—today more than ever before—is the 'central science' ".
- Levy, David M. (2002). "Research and Development". In David R. Henderson (ed.). Concise Encyclopedia of Economics (1st ed.). Library of Economics and Liberty. OCLC 317650570, 50016270 and 163149563pl:Nauki podstawowe