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Bepridil

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Bepridil
File:Bepridil.svg
Systematic (IUPAC) name
N-benzyl-N-(3-isobutoxy-2-pyrrolidin-1-yl-propyl)aniline
Clinical data
Trade names Vascor
AHFS/Drugs.com monograph
MedlinePlus a699051
  • US: C (Risk not ruled out)
Oral
Pharmacokinetic data
Bioavailability Well absorbed
Protein binding 99%
Metabolism Hepatic, CYP3A4-mediated
Half-life 42 hours
Excretion Renal
Identifiers
64706-54-3 7pxY
C08EA02
PubChem CID 2351
IUPHAR ligand 2337
DrugBank DB01244 7pxY
ChemSpider 2261 7pxY
UNII 755BO701MA 7pxY
ChEBI CHEBI:3061 7pxY
ChEMBL CHEMBL1008 7pxY
Chemical data
Formula C24H34N2O
366.54 g/mol
 14pxY (what is this?)  (verify)

Bepridil (trade name Vascor) is a calcium channel blocker once used to treat angina. It is no longer sold in the United States.

It is nonselective.[1]

It has been discussed as a possible option in the treatment of atrial fibrillation.[2]

It has been implicated in causing ventricular arrhythmia (Torsades de pointes).

References

External links

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