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Bifonazole

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Bifonazole
File:Bifonazole.svg
Systematic (IUPAC) name
(RS)-1-[Phenyl(4-phenylphenyl)methyl]-1H-imidazole
Clinical data
AHFS/Drugs.com International Drug Names
topic
Identifiers
60628-96-8 7pxY
D01AC10
PubChem CID 2378
DrugBank DB04794 7pxY
ChemSpider 2287 7pxY
UNII QYJ305Z91O 7pxY
KEGG D01775 7pxY
ChEBI CHEBI:31286 7pxN
ChEMBL CHEMBL277535 7pxY
Chemical data
Formula C22H18N2
310.392 g/mol
 14pxN (what is this?)  (verify)

Bifonazole is an imidazole antifungal drug. Bifonazole is marketed by Bayer under the trade mark Canespor in ointment form.

Mechanism of action

Bifonazole has dual mode of action. It blocks transformation of 24-methylendihydrolanosterol to desmethylsterol in fungi together with inhibition of HMG-CoA. This enables fungicidal properties against dermatophytes and distinguishes bifonazole from other antifungal drugs.

References