Open Access Articles- Top Results for Binding site
Journal of Biotechnology & BiomaterialsIsolation of Nucleotide Binding Site (NBS)-Leucine Rich Repeat (LRR) Resistant Gene Analogs (Rgas) In Arabica Coffee (Coffea Arabica L. Cv S.288)
Journal of Physical Chemistry & BiophysicsBias in Genome Scale Functional Analysis of Transcription Factors using Binding Site Data
Journal of Proteomics & BioinformaticsIn Silico Identification of Putative Proton Binding Sites of a Plasma Membrane H+-ATPase Isoform of Arabidopsis Thaliana, AHA1
Journal of Proteomics & BioinformaticsHomology Modeling and Functional Analysis of LPG2 Protein of Leishmania Strains
Journal of Computer Science & Systems BiologyAnalysis of Regulatory Genomics and Gene Expression Pattern of Medicinal Importance Genes of Helicobacter Pylori
|This article needs additional citations for verification. (July 2009)|
In biochemistry, a binding site is a region on a protein or piece of DNA or RNA to which ligands (specific molecules and/or ions) may form a chemical bond. An equilibrium exists between unbound ligands and bound ligands.
The term saturation refers to the fraction of total binding sites that are occupied at any given time. When more than one type of ligand can bind to a binding site, competition ensues.
Binding sites are often an important component of the functional characterization of biomolecules. For example, the characterization of the binding site of a substrate to an enzyme is essential to model the reaction mechanism responsible for the chemical change from substrate to product.
Binding sites on proteins can sometimes recognize other proteins. When a binding site of one protein identifies with another protein's surface, a non-covalent bond is formed between the two polypeptide (peptide) chains and a combined new protein is formed. 
A more specific type of binding site is the transcription factor binding site present on DNA. Binding sites also exist on antibodies as specifically coded regions that bind antigens based upon their structure.
- Alberts B, Bray D, Hopkin K, Johnson AD, Lewis J, Raff M, Roberts K, Walter P. (2010) Essential Cell Biology third edition.
- Binding Site - definition from Biology-Online.org
Lua error in package.lua at line 80: module 'Module:Buffer' not found.