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Open Access Articles- Top Results for Boldine

Boldine

For other uses, see Boldin.
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Boldine
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476-70-0 7pxN
ChEMBL ChEMBL388342 7pxY
ChemSpider 9748 7pxY
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C19H21NO4
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Boldine is an alkaloid of the aporphine class that can be found in the boldo tree[1] and in Lindera aggregata.[2]

Boldine has antioxidant activity that effectively protects against free radical induced lipid peroxidation or enzyme inactivation. In addition, it has alpha-adrenergic antagonist activities in vascular tissue, and it has also been reported to have hepatoprotective, cytoprotective, antipyretic and anti-inflammatory effects.[3]

References

  1. ^ O'Brien, P.; Carrasco-Pozo, C.; Speisky, H. (2006). "Boldine and its Antioxidant or Health-Promoting Properties". Chemico-Biological Interactions 159 (1): 1–17. PMID 16221469. doi:10.1016/j.cbi.2005.09.002. 
  2. ^ Han, Z.; Zheng, Y.; Chen, N.; Luan, L.; Zhou, C.; Gan, L.; Wu, Y. (2008). "Simultaneous Determination of Four Alkaloids in Lindera aggregata by Ultra-High-Pressure Liquid Chromatography–Tandem Mass Spectrometry". Journal of Chromatography A 1212 (1–2): 76–81. PMID 18951552. doi:10.1016/j.chroma.2008.10.017. 
  3. ^ Zhang, A.; Zhang, Y.; Branfman, A. R.; Baldessarini, R. J.; Neumeyer, J. L. (2007). "Advances in Development of Dopaminergic Aporphinoids". Journal of Medicinal Chemistry 50 (2): 171–181. PMID 17228858. doi:10.1021/jm060959i. 

External links

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