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Brodimoprim

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Brodimoprim
File:Brodimoprim.svg
Systematic (IUPAC) name
5-[(4-Bromo-3,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine
Clinical data
Identifiers
56518-41-3 7pxY
J01EA02
PubChem CID 68760
ChemSpider 62004 7pxY
UNII V1YC7T6LLI 7pxY
KEGG D07238 7pxY
ChEMBL CHEMBL31891 7pxY
Chemical data
Formula C13H15BrN4O2
339.188 g/mol
 14pxY (what is this?)  (verify)

Brodimoprim is a structural derivative of trimethoprim. In brodimoprim, the 4-methoxy group of trimethoprim is replaced with a bromine atom.

As trimethoprim, brodimoprim is a selective inhibitor of bacterial dihydrofolate reductase.[1]

References

  1. ^ Thomson CJ (1993). "Trimethoprim and brodimoprim resistance of gram-positive and gram-negative bacteria". J Chemother 5 (6): 458–64. PMID 8195838. 


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