Butofilolol

Butofilolol
	File:Butofilolol skeletal.svg
Systematic (IUPAC) name
	(RS)-1-[2-[3-(tert-butylamino)-2-hydroxypropoxy]-5-fluorophenyl]butan-1-one
Clinical data
Identifiers
CAS Registry Number	64552-17-6 7px
ATC code	None
PubChem	CID 68838
ChemSpider	62071 7px
UNII	4AZC6Y5A8G 7px
ChEMBL	CHEMBL157443 7px
Synonyms	CM-6805
Chemical data
Formula	C17H26FNO3
Molecular mass	311.392 g/mol
	SMILES Fc1ccc(OCC(O)CNC(C)(C)C)c(c1)C(=O)CCC;
	InChI InChI=1S/C17H26FNO3/c1-5-6-15(21)14-9-12(18)7-8-16(14)22-11-13(20)10-19-17(2,3)4/h7-9,13,19-20H,5-6,10-11H2,1-4H3 7px ; Key:NMBNQRJDEPOXCP-UHFFFAOYSA-N 7px ;
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Butofilolol (trade name Cafide) is a beta-blocker drug for the treatment of essential hypertension (high blood pressure).^[1]^[2] It is not known to be marketed anywhere.

References

^ Houin, G; Barre, J; Jeanniot, JP; Ledudal, P; Cautreels, W; Tillement, JP (1984). "Pharmacokinetics of butofilolol (CAFIDE) after repeated oral administration in man". International journal of clinical pharmacology research 4 (3): 175–83. PMID 6149195. edit
^ Toussain, P; Gay, G; Debry, G (1983). "Long-term hypotensive treatment by butofilolol". Annales de cardiologie et d'angeiologie 32 (4): 277–83. PMID 6412614. edit

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[1] Houin, G; Barre, J; Jeanniot, JP; Ledudal, P; Cautreels, W; Tillement, JP (1984). "Pharmacokinetics of butofilolol (CAFIDE) after repeated oral administration in man". International journal of clinical pharmacology research 4 (3): 175–83. PMID 6149195. edit

[2] Toussain, P; Gay, G; Debry, G (1983). "Long-term hypotensive treatment by butofilolol". Annales de cardiologie et d'angeiologie 32 (4): 277–83. PMID 6412614. edit

[1]

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Butofilolol

References

Systematic (IUPAC) name
File:Butofilolol skeletal.svg
(RS)-1-[2-[3-(tert-butylamino)-2-hydroxypropoxy]-5-fluorophenyl]butan-1-one
Clinical data
Identifiers
CAS Registry Number	64552-17-6^7pxN
ATC code	None
PubChem	CID 68838
ChemSpider	62071^7pxY
UNII	4AZC6Y5A8G^7pxY
ChEMBL	CHEMBL157443^7pxY
Synonyms	CM-6805
Chemical data
Formula	C₁₇H₂₆F N O₃
Molecular mass	311.392 g/mol
SMILES Fc1ccc(OCC(O)CNC(C)(C)C)c(c1)C(=O)CCC
InChI InChI=1S/C17H26FNO3/c1-5-6-15(21)14-9-12(18)7-8-16(14)22-11-13(20)10-19-17(2,3)4/h7-9,13,19-20H,5-6,10-11H2,1-4H3 ^7pxY Key:NMBNQRJDEPOXCP-UHFFFAOYSA-N ^7pxY
14pxN (what is this?) (verify)