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Open Access Articles- Top Results for Butyrophenone

Butyrophenone

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Butyrophenone

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This page is a soft redirect. Names

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IUPAC name
1-phenylbutan-1-one
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495-40-9 7pxY ChEMBL ChEMBL193524 7pxY ChemSpider 9893 7pxY Jmol-3D images Image
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C10H12O Molar mass 148.20 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Butyrophenone is a chemical compound; some of its derivatives (called commonly butyrophenones) are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics.[1]

Butyrophenones are a class of pharmaceutical drugs derived from butyrophenone.

Examples include:

The atypical antipsychotic risperidone, although not a butyrophenone, was developed with the structures of benperidol and ketanserin as a basis.

Ketocaine is a butyrophenone local anesthetic.

References

  1. ^ a b c Keith Parker; Laurence Brunton; Goodman, Louis Sanford; Lazo, John S.; Gilman, Alfred (2006). Goodman & Gilman's The Pharmacological Basis of Therapeutics (11th ed.). New York: McGraw-Hill. ISBN 0071422803. 
  2. ^ Chronicles of Drug Discovery Vol 2


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