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Open Access Articles- Top Results for CACNA1G

CACNA1G

Template:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/row
Identifiers
SymbolsCACNA1G ; Ca(V)T.1; Cav3.1; NBR13
External IDsOMIM604065 MGI1201678 HomoloGene22544 IUPHAR: 535 ChEMBL: 4641 GeneCards: CACNA1G Gene
Orthologs
SpeciesHumanMouse
Entrez891312291
EnsemblENSG00000006283ENSMUSG00000020866
UniProtO43497Q5SUG1
RefSeq (mRNA)NM_001256324NM_001112813
RefSeq (protein)NP_001243253NP_001106284
Location (UCSC)Chr 17:
48.64 – 48.7 Mb
Chr 11:
94.41 – 94.47 Mb
PubMed search[1][2]

Calcium channel, voltage-dependent, T type, alpha 1G subunit, also known as CACNA1G or Cav3.1 is a protein which in humans is encoded by the CACNA1G gene.[1][2][3]

Function

Voltage-dependent calcium channels can be distinguished based on their voltage-dependence, deactivation, and single-channel conductance. Low-voltage-activated calcium channels are referred to as 'T' type because their currents are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing.[1]

Interactive pathway map

Click on genes, proteins and metabolites below to link to respective Wikipedia articles. [§ 1]

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  1. ^ The interactive pathway map can be edited at WikiPathways: "NicotineActivityonChromaffinCells_WP1603". 

See also

References

  1. ^ a b "Entrez Gene: CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit". 
  2. ^ Perez-Reyes E, Cribbs LL, Daud A, Lacerda AE, Barclay J, Williamson MP, Fox M, Rees M, Lee JH (February 1998). "Molecular characterization of a neuronal low-voltage-activated T-type calcium channel". Nature 391 (6670): 896–900. PMID 9495342. doi:10.1038/36110. 
  3. ^ Catterall WA, Perez-Reyes E, Snutch TP, Striessnig J (December 2005). "International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels". Pharmacol. Rev. 57 (4): 411–25. PMID 16382099. doi:10.1124/pr.57.4.5. 

External links

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